Article
Chromosome 1 alterations in breast cancer: allelic loss on 1p and 1q is related to lymphogenic metastases and poor prognosis.
Genes, chromosomes & cancer - 1 Nov 1992
Borg A, Zhang Q X, Olsson H, Wenngren E
Abstract excerpt
The development of human breast cancer is characterized by a variety of genetic alterations, and cytogenetic analyses have documented the consistent involvement of both arms of chromosome 1. In the present study, molecular markers detecting restriction fragment length polymorphisms were used in p...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Biomarkers, Tumor
- Breast Neoplasms
- Chromosome Aberrations
- Chromosomes, Human, Pair 1
- DNA Probes
- Female
- Genetic Markers
- Humans
- Lymphatic Metastasis
- Male
- Membrane Glycoproteins
- Middle Aged
- Mucin-1
- Mucins