Article
Mutant p53 expression and DNA analysis in human breast cancer comparison with conventional clinicopathological parameters.
Anticancer research - 1 Jan 2000
Rosanelli G P, Steindorfer P, Wirnsberger G H, Klimpfinger M, Ratschek M, Puerstner P, Auner H, Berhold A
Abstract excerpt
Scientific research evaluates the prognostic importance of 53 expression and DNA flow cytometry controversially. To evaluate the prognostic relevance of mutant p53 protein overexpression and DNA flow cytometry in primary breast cancer we correlated these factors with the common prognostic parameters such as tumor size, lymph node status, grading, menopausal status and receptor status. Human breast cancer...
Topics
- Adult
- Aged
- Aneuploidy
- Biomarkers, Tumor
- Breast Neoplasms
- DNA, Neoplasm
- Female
- Flow Cytometry
- Gene Expression
- Humans
- Lymphatic Metastasis
