Article
p53 status in breast carcinomas revealed by FASAY correlates well with p53 protein accumulation determined by immunohistochemistry.
Neoplasma - 1 Jan 1999
Smardová J, Vagunda V, Jandáková E, Vagundová M, Koukalová H, Kovarík J, Zaloudík J
Abstract excerpt
The prognostic and predictive value of p53 mutation in breast cancer is still conflicting. The choice of the p53 status detection method may account for some discrepancies. In this pilot study we compared two differently-based methods for detection of p53 alteration in 32 breast carcinoma samples: the immunohistochemical method using Bp53, DO1 and DO11 monoclonal antibodies for analysis of the p53 protein...
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