Article
Quantification and characterization of total cellular p53 protein in colorectal cancer.
Cytometry - 1 Jan 1998
Tominaga O, Hammel P, Hamelin R, Nagawa H, Muto T, Remvikos Y
Abstract excerpt
Immunochemical methods were developed for the optimal detection and characterization of total cellular p53 protein expression, both in the nuclear-attached and soluble fractions of colorectal cancers, in order to improve the correlation between protein deregulation and gene status. Seventy colorectal carcinomas were studied using 3 monoclonal antibodies in a sensitive analyzing system combining flow cytometry...
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