Article
p53 oncoprotein as a prognostic indicator in patients with breast cancer.
Anticancer research - 1 Jan 2000
Molina R, Segui M A, Climent M A, Bellmunt J, Albanelll J, Fernandez M, Filella X, Jo J, Gimenez N, Iglesias E, Miralles M, Alonso C, Peiro G, Perez-Picañol E, Ballesta A M
Abstract excerpt
UNLABELLED: p53 is a tumor suppressor gene located on the human chromosome 17 that is thought to regulate (suppress) the proliferation of normal cells. The mutant protein accumulates in the nuclei of tumor cells that may then have a proliferative advantage over normal cells. The purpose of this s...
Topics
- Biomarkers, Tumor
- Breast Neoplasms
- Humans
- Lymphatic Metastasis
- Middle Aged
- Mutation
- Neoplasms, Hormone-Dependent
- Prognosis
- Tumor Suppressor Protein p53
