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Article

A proliferative p53-responsive element mediates tumor necrosis factor alpha induction of the human immunodeficiency virus type 1 long terminal repeat.

Molecular and cellular biology - 1 Jun 1995

Gualberto A, Hixon M L, Finco T S, Perkins N D, Nabel G J, Baldwin A S

Abstract excerpt

Transforming mutants of the p53 tumor suppressor gene can positively regulate transcription from several promoters that do not contain known p53 binding sites. Here, we report the identification of a novel p53 binding site in the human immunodeficiency virus long terminal repeat that specifically mediates mutant p53 transactivation. This DNA element was bound by endogenous Jurkat p53 when these cells were...

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Identifiers

PMID: 7760842
DOI: 10.1128/MCB.15.6.3450
PMCID: PMC230580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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