HLA and ethnic associations among systemic sclerosis patients with anticentromere antibodies.

doi:10.1016/0198-8859(94)00078-5

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Article

HLA and ethnic associations among systemic sclerosis patients with anticentromere antibodies.

Human immunology - 1 Jan 1995

Morel P A, Chang H J, Wilson J W, Conte C, Falkner D, Tweardy D J, Medsger T A

Abstract excerpt

SSc with ACAs is characterized by limited cutaneous involvement and, in most patients, a mild protracted course. We have studied 104 SSc patients, 47 with ACAs and 57 who were negative for both ACAs and anti-topo I antibodies, for HLA-DR and -DQ associations using DNA typing techniques. Normal co...

Topics

Adult
Alleles
Antibodies, Antinuclear
Autoantibodies
Centromere
DNA Topoisomerases, Type I
Disease Susceptibility
Ethnicity
Europe
Europe, Eastern
Female
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DQ Antigens

Humans

Male

Middle Aged

Pennsylvania

Scleroderma, Systemic

Source

Open in PubMed

Identifiers

PMID: 7751158
DOI: 10.1016/0198-8859(94)00078-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7751158-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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