Influence of ethnic background on clinical and serologic features in patients with systemic sclerosis and anti-DNA topoisomerase I antibody.

doi:10.1002/1529-0131(199904)42:3<465::AID-ANR11>3.0.CO;2-Y

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Article

Influence of ethnic background on clinical and serologic features in patients with systemic sclerosis and anti-DNA topoisomerase I antibody.

Arthritis and rheumatism - 1 Mar 1999

Kuwana M, Kaburaki J, Arnett F C, Howard R F, Medsger T A, Wright T M

Abstract excerpt

OBJECTIVE: To investigate the effect of ethnicity on clinical and serologic expression in patients with systemic sclerosis (SSc) and anti-DNA topoisomerase I (anti-topo I) antibody. METHODS: Clinical and serologic features, as well as HLA class II allele frequencies, were compared among 47 North American white, 15 North American black, 43 Japanese, and 12 Choctaw Native American SSc patients with anti-topo I...

Topics

Adult
Aged
Alleles
Antibodies, Antinuclear
Antibody Specificity
Asian People
B-Lymphocytes
DNA Topoisomerases, Type I
Disease Progression
Epitopes
Female
HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DR Antigens

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DRB1 Chains

Histocompatibility Antigens Class II

Humans

Immunoglobulin A

Source

Open in PubMed

Identifiers

PMID: 10088769
DOI: 10.1002/1529-0131(199904)42:3<465::AID-ANR11>3.0.CO;2-Y

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