Article
HLA class II genes associated with anticentromere antibody in Japanese patients with systemic sclerosis (scleroderma).
Annals of the rheumatic diseases - 1 Dec 1995
Kuwana M, Okano Y, Kaburaki J, Inoko H
Abstract excerpt
OBJECTIVE: To define further HLA class II gene associations with anticentromere antibody (ACA), a major serum antinuclear antibody in patients with systemic sclerosis (SSc). METHODS: HLA class II genes were determined using polymerase chain reaction/restriction fragment length polymorphisms in 94 Japanese patients with SSc (22 ACA positive and 72 ACA negative) and 50 race matched normal control subjects. RESULTS:...
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