HLA and clinical associations in systemic sclerosis patients with anti-Th/To antibodies.

doi:10.1002/1529-0131(199801)41:1<74::AID-ART10>3.0.CO;2-C

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Article

HLA and clinical associations in systemic sclerosis patients with anti-Th/To antibodies.

Arthritis and rheumatism - 1 Jan 1998

Falkner D, Wilson J, Medsger T A, Morel P A

Abstract excerpt

OBJECTIVE: To determine the clinical and immunogenetic features of systemic sclerosis (SSc) patients with anti-Th/To autoantibodies. METHODS: HLA class II alleles were determined by DNA oligotyping in a large group of SSc patients with anticentromere antibodies (ACA), anti-topoisomerase I (anti-t...

Topics

Alleles
Autoantibodies
Centromere
DNA Topoisomerases, Type I
Genetic Linkage
HLA-DQ Antigens
HLA-DR Antigens
Histocompatibility Testing
Humans
RNA Polymerase III
Scleroderma, Systemic

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