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Article

Transcriptional repression in normal human keratinocytes by wild-type and mutant p53.

Cancer letters - 4 May 1995

Alvarez-Salas L M, Velazquez A, Lopez-Bayghen E, Woodworth C D, Garrido E, Gariglio P, DiPaolo J A

Abstract excerpt

Wild-type p53 is a nuclear phosphoprotein that inhibits cell proliferation and represses transcriptionally most TATA box-containing promoters in transformed or tumor-derived cell lines. This study demonstrates that p53 alters transcription of the long control region (LCR) of human papillomavirus type 18 (HPV-18). Wild-type and mutant p53 143Val to Ala repressed the HPV-18 LCR promoter in normal human...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 7750099
DOI: 10.1016/0304-3835(95)03721-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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