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Article

Transcriptional repression in normal human keratinocytes by wild-type and mutant p53.

Cancer letters - 4 May 1995

Alvarez-Salas L M, Velazquez A, Lopez-Bayghen E, Woodworth C D, Garrido E, Gariglio P, DiPaolo J A

Abstract excerpt

Wild-type p53 is a nuclear phosphoprotein that inhibits cell proliferation and represses transcriptionally most TATA box-containing promoters in transformed or tumor-derived cell lines. This study demonstrates that p53 alters transcription of the long control region (LCR) of human papillomavirus...

Topics

Cell Line
Cervix Uteri
Female
Genes, p53
Humans
Keratinocytes
Mutation
Papillomaviridae
Promoter Regions, Genetic
Suppression, Genetic
Transcription, Genetic
Transfection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7750099
DOI: 10.1016/0304-3835(95)03721-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7750099-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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