Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters.

Journal of virology - 1 Jun 1990

Romanczuk H, Thierry F, Howley P M

Abstract excerpt

cis-Acting elements involved in E2 modulation of human papillomavirus type 16 (HPV-16) P97 promoter activity and HPV-18 P105 promoter activity were examined. In transfected primary human keratinocytes, each promoter had a basal activity that could be repressed by the bovine papillomavirus type 1 E2 gene product. Mutational analysis of the E2-binding sites in the long control region upstream of each promoter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cells, Cultured
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Promoter Regions, Genetic

Share to Transcription, Genetic

Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 2159546
DOI: 10.1128/JVI.64.6.2849-2859.1990
PMCID: PMC249467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters.PMID 2159546Read ↗

Dose-dependent regulation of the early promoter of human papillomavirus type 18 by the viral E2 proteinSemantic proximity Read ↗

The E8 Domain Confers a Novel Long-Distance Transcriptional Repression Activity on the E8^E2C Protein of High-Risk Human Papillomavirus Type 31Semantic proximity Read ↗

Different mechanisms contribute to the E2-mediated transcriptional repression of human papillomavirus type 18 viral oncogenesSemantic proximity Read ↗

The E8 <sup>∧</sup> E2 Gene Product of Human Papillomavirus Type 16 Represses Early Transcription and Replication but Is Dispensable for Viral Plasmid Persistence in KeratinocytesSemantic proximity Read ↗

Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity.Semantic proximity Read ↗

Cellular transcription factors regulate human papillomavirus type 16 gene expression by binding to a subset of the DNA sequences recognized by the viral E2 protein.Semantic proximity Read ↗

The Viral E8^E2C Repressor Limits Productive Replication of Human Papillomavirus 16Semantic proximity Read ↗

Sequence analysis of the long control region of human papillomavirus type 16 variants and functional consequences for P97 promoter activitySemantic proximity Read ↗

Two AP1 sites binding JunB are essential for human papillomavirus type 18 transcription in keratinocytesSemantic proximity Read ↗

Low-affinity E2-binding site mediates downmodulation of E2 transactivation of the human papillomavirus type 8 late promoter.Semantic proximity Read ↗

The viral transcriptional regulatory region upstream of the E6 and E7 genes is a major determinant of the differential immortalization activities of human papillomavirus types 16 and 18Semantic proximity Read ↗

Different P105 promoter activities among natural variants of human papillomavirus type 18.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.