Article
Apolipoprotein E polymorphism and susceptibility to Alzheimer's disease.
Human biology - 1 Apr 1995
Kamboh M I
Abstract excerpt
Apolipoprotein E (apoE, protein; APOE, gene) plays an important role in lipoprotein metabolism by acting as a ligand for two specific cell receptors to mediate the uptake of apoE-containing lipoproteins by cells. The APOE gene, located on chromosome 19, exhibits a genetic polymorphism with three common alleles, APOE*2, APOE*3, and APOE*4, which show marked variation in their distribution among various ethnic...
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