Apolipoprotein E polymorphism and susceptibility to Alzheimer's disease.

Article

Apolipoprotein E polymorphism and susceptibility to Alzheimer's disease.

Human biology - 1 Apr 1995

Kamboh M I

Abstract excerpt

Apolipoprotein E (apoE, protein; APOE, gene) plays an important role in lipoprotein metabolism by acting as a ligand for two specific cell receptors to mediate the uptake of apoE-containing lipoproteins by cells. The APOE gene, located on chromosome 19, exhibits a genetic polymorphism with three...

Topics

Alleles
Alzheimer Disease
Apolipoprotein E2
Apolipoprotein E3
Apolipoprotein E4
Apolipoproteins E
Chromosomes, Human, Pair 19
Genetic Variation
Humans
Lipoproteins
Polymorphism, Genetic
Protein Binding
Risk Factors

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