Article
Apolipoprotein E, amyloid, and Alzheimer disease.
Molecular interventions - 1 Oct 2002
Bales K R, Dodart J C, DeMattos R B, Holtzman D M, Paul S M
Abstract excerpt
Despite important inroads into the molecular pathology of Alzheimer disease, effective long-term treatment for the condition remains elusive. Among the many gene products that are recognized as factors in the disease is apolipoprotein ( (apoE). The risk that specific isoforms of apoE pose with regard to Alzheimer Disease clearly varies, and so the roles that apoE plays in the brain will be crucial to a full...
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