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Article

Human apolipoprotein E: the Alzheimer's disease connection.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 1996

Weisgraber K H, Mahley R W

Abstract excerpt

Human apolipoprotein (apo) E, long known for its prominent role in cholesterol transport and plasma lipoprotein metabolism, has recently emerged as a major genetic risk factor for Alzheimer's disease, a neurodegenerative disorder. In a variety of populations worldwide, one of the three common all...

Topics

Alzheimer Disease
Apolipoproteins E
Cytoskeleton
Genotype
Heparin
Humans
Neurons
Protein Conformation
Proteoglycans
Receptors, LDL
Structure-Activity Relationship
tau Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8940294
DOI: 10.1096/fasebj.10.13.8940294

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8940294-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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