Article
Partial restoration of pre-transformation levels of lysyl oxidase and transin mRNAs in phenotypic ras revertants.
Molecular carcinogenesis - 1 Apr 1995
Oberhuber H, Seliger B, Schäfer R
Abstract excerpt
Neoplastic transformation mediated by ras oncogenes is associated with deregulated expression of genes encoding, for example, various proteases, lysyl oxidase, and smooth-muscle alpha-actin. To define the role of these genes in the initiation or maintenance of the ras-transformed state, we compar...
Topics
- Animals
- Blotting, Western
- Cathepsin L
- Cathepsins
- Cell Line
- Cell Transformation, Neoplastic
- Collagenases
- Cysteine Endopeptidases
- Endopeptidases
- Gene Expression
- Genes, ras
- Matrix Metalloproteinase 1
- Matrix Metalloproteinase 3
- Metalloendopeptidases
- Neoplasm Proteins
- Phenotype
- Precancerous Conditions
- Protein-Lysine 6-Oxidase