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Article

Accumulation of p53 tumor suppressor gene protein: an independent marker of prognosis in breast cancers.

Journal of the National Cancer Institute - 3 Jun 1992

Thor A D, Moore DH I I, Edgerton S M, Kawasaki E S, Reihsaus E, Lynch H T, Marcus J N, Schwartz L, Chen L C, Mayall B H

Abstract excerpt

BACKGROUND: Mutations of the tumor suppressor gene p53 have been identified in breast cancer cell lines, and some breast carcinomas are detectable by immunohistochemical assay because of p53 protein accumulation. PURPOSE: This study was designed to determine whether p53 protein accumulation in breast cancers correlates with p53 gene mutation, with survival, and with five pathobiologic factors associated with...

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Identifiers

PMID: 1317462
DOI: 10.1093/jnci/84.11.845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Accumulation of p53 tumor suppressor gene protein: an independent marker of prognosis in breast cancers.PMID 1317462Read ↗

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