Parkinson's disease and apolipoprotein E: possible association with dementia but not age at onset.

doi:10.1006/geno.2002.6707

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Article

Parkinson's disease and apolipoprotein E: possible association with dementia but not age at onset.

Genomics - 1 Mar 2002

Parsian Abbas, Racette Brad, Goldsmith L Jane, Perlmutter Joel S

Abstract excerpt

Idiopathic Parkinson's disease (PD) is an age-dependent, neurodegenerative condition frequently associated with dementia. Although it is predominantly a sporadic disease, 20-30% of cases are familial, suggesting a complex mode of inheritance. Apolipoprotein E (APOE) allele epsilon4 has been assoc...

Topics

Adult
Age of Onset
Aged
Aged, 80 and over
Apolipoproteins E
Dementia
Female
Genetic Predisposition to Disease
Humans
Middle Aged
Parkinson Disease
Polymorphism, Genetic
Survival Analysis

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