Article
Parkinson's disease and apolipoprotein E: possible association with dementia but not age at onset.
Genomics - 1 Mar 2002
Parsian Abbas, Racette Brad, Goldsmith L Jane, Perlmutter Joel S
Abstract excerpt
Idiopathic Parkinson's disease (PD) is an age-dependent, neurodegenerative condition frequently associated with dementia. Although it is predominantly a sporadic disease, 20-30% of cases are familial, suggesting a complex mode of inheritance. Apolipoprotein E (APOE) allele epsilon4 has been associated with familial and sporadic late-onset senile dementia of the Alzheimer's type. To investigate the role of this...
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