No association between apolipoprotein E epsilon4 allele and the age of onset in type I familial amyloid polyneuropathy.

doi:10.1016/0304-3940(96)12344-2

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Article

No association between apolipoprotein E epsilon4 allele and the age of onset in type I familial amyloid polyneuropathy.

Neuroscience letters - 9 Feb 1996

Satoh S, Tokuda T, Ikeda S, Sekijima Y, Yanagisawa N, Hidaka H, Kametani F

Abstract excerpt

It has been shown that the Apolipoprotein E (ApoE) epsilon4 allele increases the risk of developing Alzheimer's disease (AD) and lowers the age of its onset. ApoE has also been suggested to be a common facilitating factor in the different types of amyloidoses. However, the association of ApoE eps...

Topics

Age of Onset
Alleles
Amyloid Neuropathies
Apolipoprotein E4
Apolipoproteins E
Base Sequence
Chromosome Aberrations
Chromosome Disorders
Genotype
Humans
Molecular Sequence Data

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