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Article

Conformational changes in mutant lysozymes detected with monoclonal antibody.

FEBS letters - 28 Aug 1995

Kato A, Shimizu T, Saga S

Abstract excerpt

A monoclonal antibody (mAb) against hen egg white lysozyme (HEWL) with the exquisitely sensitive specificity to native conformation was prepared to detect the conformational changes in mutant lysozymes constructed by genetic modification in a yeast expression system. The binding of mAb with lysozyme was decreased both by denaturation with heat and guanidine-HCl, corresponding to the denaturation curves of...

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Identifiers

PMID: 7664875
DOI: 10.1016/0014-5793(95)00846-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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