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Article

Influence of mutations of the N-cap residue, Gly4, on stability and structure of hen lysozyme.

Journal of biochemistry - 1 Jul 1997

Motoshima H, Ueda T, Masumoto K, Hashimoto Y, Chijiiwa Y, Imoto T

Abstract excerpt

Hen lysozyme, with three alpha-helices (A, B, and C), is a c-type lysozyme. In these lysozymes, Ser24 and Asp88 located at the N-cap position in the B- and C-helix, respectively, are mostly conserved, but residue 4 at the N-cap position in A-helix is variable. To investigate the effect of mutation at position 4 on the stability of hen lysozyme, we prepared five mutant lysozymes and examined their stabilities and...

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PMID: 9276667
DOI: 10.1093/oxfordjournals.jbchem.a021736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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