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Article

Distinct centromere domain structures with separate functions demonstrated in live fission yeast cells.

Journal of cell science - 1 Oct 2003

Appelgren Henrik, Kniola Barbara, Ekwall Karl

Abstract excerpt

Fission yeast (Saccharomyces pombe) centromere DNA is organized in a central core region flanked on either side by a region of outer repeat (otr) sequences. The otr region is known to be heterochromatic and bound by the Swi6 protein whereas the central core region contains an unusual chromatin structure involving the histone H3 variant Cnp1 (S. pombe CENP-A). The central core is the base for formation of the...

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PMID: 12928332
DOI: 10.1242/jcs.00707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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