Article
Tumour suppressor p53 and Rb genes in human hepatocellular carcinoma.
Annals of the Academy of Medicine, Singapore - 1 Jan 1996
Lin Y, Shi C Y, Li B, Soo B H, Mohammed-Ali S, Wee A, Oon C J, Mack P O, Chan S H
Abstract excerpt
Aberrations of the p53 and Rb tumour suppressor genes were examined in 12 human hepatocellular carcinoma (HCC)-derived cell lines from different geographic areas and 9 local HCCs by restriction fragment length polymorphisms (RFLP), polymerase chain reaction-single-strand conformation polymorphism...
Topics
- Animals
- Base Sequence
- Carcinoma, Hepatocellular
- Cats
- DNA
- Genes, Retinoblastoma
- Genes, Tumor Suppressor
- Genes, p53
- Hepatitis B
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Tumor Cells, Cultured
