Article
Tumour suppressor p53 and Rb genes in human hepatocellular carcinoma.
Annals of the Academy of Medicine, Singapore - 1 Jan 1996
Lin Y, Shi C Y, Li B, Soo B H, Mohammed-Ali S, Wee A, Oon C J, Mack P O, Chan S H
Abstract excerpt
Aberrations of the p53 and Rb tumour suppressor genes were examined in 12 human hepatocellular carcinoma (HCC)-derived cell lines from different geographic areas and 9 local HCCs by restriction fragment length polymorphisms (RFLP), polymerase chain reaction-single-strand conformation polymorphisms (PCR-SSCP) and DNA sequencing. The relationships between genetic changes and hepatitis B virus (HBV) DNA integration...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
