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Article

Molecular dissection of the role of the membrane domain in the regulated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

The Journal of biological chemistry - 11 Aug 1995

Kumagai H, Chun K T, Simoni R D

Abstract excerpt

We have previously shown that the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase from hamster contains all of the sequences required for both localization to the endoplasmic reticulum and regulated degradation of the enzyme. It has been reported that the enzymatic ac...

Topics

Amino Acid Sequence
Animals
CHO Cells
Cricetinae
Hydroxymethylglutaryl CoA Reductases
Molecular Sequence Data
Phenotype
Sea Urchins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7642576
DOI: 10.1074/jbc.270.32.19107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7642576-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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