Abnormal regulation of low density lipoprotein-sensitive events in a cholesterol transport mutant.

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Article

Abnormal regulation of low density lipoprotein-sensitive events in a cholesterol transport mutant.

The Journal of biological chemistry - 15 Aug 1993

Dahl N K, Gutheil W G, Liscum L

Abstract excerpt

We have isolated and characterized Chinese hamster ovary cell mutants defective in the intracellular transport of low density lipoprotein (LDL)-derived cholesterol (Dahl, N. K., Reed, K. L., Daunais, M. A., Faust, J. R., and Liscum, L. (1992) J. Biol. Chem. 267, 4889-4896). Mutant 2-2, which exhi...

Topics

Animals
Biological Transport
CHO Cells
Cholesterol
Cricetinae
Esterification
Hydroxycholesterols
Hydroxymethylglutaryl CoA Reductases
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Kinetics
Lipoproteins, LDL
Mevalonic Acid
Mutation
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 8349588

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8349588-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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