Article
A heteroallelic Drosophila insulin-like receptor mutant and its use in validating physiological activities of food constituents.
Biochemical and biophysical research communications - 3 May 2013
Kayashima Yasunari, Sato Ayaka, Kumazawa Shigenori, Yamakawa-Kobayashi Kimiko
Abstract excerpt
Here we report an additional Drosophila transheterozygote InR(GS15311)/InR(GS50346) carrying two different P-element-inducible alleles of insulin-like receptor gene (InR). InR(GS15311)/InR(GS50346) flies exhibit the following phenotypes previously reported in InR and insulin/IGF-1 signaling (IIS) pathway-related gene mutants: small bodies, developmental delay, shortened lifespan, and increased fasting resistance....
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