Article
Cell proliferation and DNA replication defects in a Drosophila MCM2 mutant.
Genes & development - 15 Jul 1995
Treisman J E, Follette P J, O'Farrell P H, Rubin G M
Abstract excerpt
The yeast MCM2, MCM3, and MCM5/CDC46 genes are required for DNA replication and have been proposed to act as factors that license the DNA for one and only one round of replication per cell cycle. We have identified a Drosophila gene, DmMCM2, that is highly homologous to MCM2. A P-element insertio...
Topics
- Amino Acid Sequence
- Animals
- Cell Division
- Chromosomal Proteins, Non-Histone
- DNA Replication
- Drosophila melanogaster
- Fungal Proteins
- Gene Expression Regulation, Developmental
- Genes, Fungal
- Genes, Insect
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Phenotype
- S Phase
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid