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Article

Drosophila Mcm10 is required for DNA replication and differentiation in the compound eye.

PloS one - 1 Jan 2014

Vo Nicole, Taga Ayano, Inaba Yasuhiro, Yoshida Hideki, Cotterill Sue, Yamaguchi Masamitsu

Abstract excerpt

Mini chromosome maintenance 10 (Mcm10) is an essential protein, which is conserved from S. cerevisiae to Drosophila and human, and is required for the initiation of DNA replication. Knockdown of Drosophila Mcm10 (dMcm10) by RNA interference in eye imaginal discs induces abnormal eye morphology (rough eye phenotype), and the number of ommatidia is decreased in adult eyes. We also observed a delay in the S phase...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24686397
DOI: 10.1371/journal.pone.0093450
PMCID: PMC3970972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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