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Article

Genetic analysis of the Drosophila cdc2 homolog.

Development (Cambridge, England) - 1 Jan 1993

Stern B, Ried G, Clegg N J, Grigliatti T A, Lehner C F

Abstract excerpt

We have identified mutations in the Drosophila cdc2 gene. The recessive lethality of these mutant alleles was rescued after P-element-mediated transformation with a genomic cdc2 fragment. Sequence analysis of amorphic alleles revealed non-conservative exchanges in evolutionary conserved positions...

Topics

Amino Acid Sequence
Animals
Base Sequence
CDC2 Protein Kinase
Cell Division
Drosophila
Genes, Insect
Genes, Lethal
Genes, Recessive
Microscopy, Fluorescence
Mitosis
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Phenotype

Source

Identifiers

PMID: 8223248
DOI: 10.1242/dev.117.1.219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8223248-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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