Article
Multiple functions for Drosophila Mcm10 suggested through analysis of two Mcm10 mutant alleles.
Genetics - 1 Aug 2010
Apger Jennifer, Reubens Michael, Henderson Laura, Gouge Catherine A, Ilic Nina, Zhou Helen H, Christensen Tim W
Abstract excerpt
DNA replication and the correct packaging of DNA into different states of chromatin are both essential processes in all eukaryotic cells. High-fidelity replication of DNA is essential for the transmission of genetic material to cells. Likewise the maintenance of the epigenetic chromatin states is essential to the faithful reproduction of the transcriptional state of the cell. It is becoming more apparent that...
Topics
- Alleles
- Animals
- Animals, Genetically Modified
- Binding Sites
- Blotting, Western
- Cell Cycle Proteins
- Chromosomal Proteins, Non-Histone
- Chromosomes, Insect
- DNA Replication
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Gene Expression Regulation, Developmental