Article
Depletion of minichromosome maintenance protein 5 in the zebrafish retina causes cell-cycle defect and apoptosis.
Proceedings of the National Academy of Sciences of the United States of America - 20 Dec 2005
Ryu Soojin, Holzschuh Jochen, Erhardt Simone, Ettl Anne-Kathrin, Driever Wolfgang
Abstract excerpt
In multicellular organisms, the control of genome duplication and cell division must be tightly coordinated. Essential roles of the minichromosome maintenance (MCM) proteins for genome duplication have been well established. However, no genetic model has been available to address the function of MCM proteins in the context of vertebrate organogenesis. Here, we present positional cloning of a zebrafish mcm5...
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