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Article

Triple-label hybridization assay for type-1 diabetes-related HLA alleles.

BioTechniques - 1 May 1995

Sjöroos M, Iitiä A, Ilonen J, Reijonen H, Lövgren T

Abstract excerpt

We describe a method for the detection of two type 1 (insulin-dependent) diabetes susceptibility (*0201, *0302) alleles and two protective (*0301, *0602/0603) alleles of the HLA-DQB1 gene on the human major histocompatibility complex (MHC). The test is based on DNA amplification with PCR followed...

Topics

Alleles
Base Sequence
Biotin
DNA
DNA Probes
Diabetes Mellitus, Type 1
Europium
Fluorometry
Genotype
HLA-DQ Antigens
HLA-DQ beta-Chains
Humans
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nucleic Acid Hybridization

Polymerase Chain Reaction

Polymorphism, Genetic

Samarium

Sensitivity and Specificity

Source

Identifiers

PMID: 7619493

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7619493-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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