Article
T cell recognition of major histocompatibility complex class II complexes with invariant chain processing intermediates.
The Journal of experimental medicine - 1 Nov 1995
Morkowski S, Goldrath A W, Eastman S, Ramachandra L, Freed D C, Whiteley P, Rudensky AYu
Abstract excerpt
Peptides from the lumenal portion of invariant chain (Ii) spanning residues 80-106 (class II-associated Ii peptide [CLIP]) are found in association with several mouse and human major histocompatibility complex (MHC) class II allelic variants in wild-type and presentation-deficient mutant cells. T...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antigen Presentation
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- Binding Sites
- Epitopes
- Glycine
- Histocompatibility Antigens Class II
- Humans
- Hybrid Cells
- Leupeptins
- Lysine
- Macromolecular Substances
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL