Article
A general model of invariant chain association with class II major histocompatibility complex proteins.
Proceedings of the National Academy of Sciences of the United States of America - 29 Aug 1995
Lee C, McConnell H M
Abstract excerpt
The binding of invariant chain to major histocompatibility complex (MHC) proteins is an important step in processing of MHC class II proteins and in antigen presentation. The question of how invariant chain can bind to all MHC class II proteins is central to understanding these processes. We have...
Topics
- Alleles
- Amino Acid Sequence
- Antigens, Differentiation, B-Lymphocyte
- Histocompatibility Antigens Class II
- Humans
- Models, Molecular
- Molecular Sequence Data
- Protein Conformation