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Article

Loss of heterozygosity at 9p21 loci and mutations of the MTS1 and MTS2 genes in human lung cancers.

International journal of cancer - 27 Nov 1995

Shimizu T, Sekiya T

Abstract excerpt

To elucidate the involvement of abnormalities of the MTS1/p16 and MTS2/p15 genes located at chromosomal region 9p21 in human lung cancers, we analyzed DNA from 30 primary lung cancers and detected loss of heterozygosity at the 9p21-p23 region in 15 tumors. Single-strand-conformation-polymorphism analysis of polymerase-chain-reaction products from the MTS1 and MTS2 genes and determination of the nucleotide...

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Identifiers

PMID: 7591275
DOI: 10.1002/ijc.2910630503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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