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Article

Contribution of chromosome 9p21-22 deletion to the progression of human renal cell carcinoma.

Japanese journal of cancer research : Gann - 1 Sept 1995

Kinoshita H, Yamada H, Ogawa O, Kakehi Y, Osaka M, Nakamura E, Mishina M, Habuchi T, Takahashi R, Sugiyama T

Abstract excerpt

To investigate the possible role of genomic aberrations of chromosome 9p21-22 in the tumorigenesis of human renal cell carcinoma (RCC), 10 RCC cell lines, 55 primary RCCs and 5 metastatic lesions were studied by Southern blotting and polymerase chain reaction-based analysis. Nine of 10 RCC cell l...

Topics

Alleles
Carcinoma, Renal Cell
Carrier Proteins
Chromosome Deletion
Chromosomes, Human, Pair 9
Cyclin-Dependent Kinase Inhibitor p16
Disease Progression
Genes, Tumor Suppressor
Heterozygote
Homozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kidney Neoplasms

Polymerase Chain Reaction

Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 7591954
DOI: 10.1111/j.1349-7006.1995.tb03087.x
PMCID: PMC5920923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7591954-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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