Article
Microsatellite alteration in histologically normal lung tissue of patients with non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Nov 2000
Park J Y, Jeon H S, Park S H, Park T I, Son J W, Kim C H, Park J H, Kim I S, Jung T H, Jun S H
Abstract excerpt
Microsatellite alteration (MSA) has been observed in a fraction of non-small cell lung cancer (NSCLC). Most prior studies regarding MSA in lung cancer have usually used adjacent non-malignant lung tissues as a source of constitutional DNA. However, these normal tissues might have genetic alterations because the entire field of bronchial tree is exposed to the same carcinogenic insult. The aim of this study was to...
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