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Article

Clonal Genetic Alterations in the Lungs of Current and Former Smokers

18 Jun 1997

Abstract excerpt

BACKGROUND AND PURPOSE: Genetic damage has been identified at multiple chromosomal sites (i.e., loci) in lung cancer cells. We questioned whether similar damage could be detected in the bronchial epithelial cells of chronic smokers who do not have this disease. METHODS: Biopsy specimens from six different bronchial regions were obtained from 54 chronic smokers (40 current smokers and 14 former smokers). The...

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Identifiers

PMID: 9196251
DOI: 10.1093/jnci/89.12.857

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