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Article

Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer.

Genes, chromosomes & cancer - 1 Dec 2005

Sato Masamitsu, Takahashi Kenji, Nagayama Kazuhiro, Arai Yasuhito, Ito Nobue, Okada Mitsumasa, Minna John D, Yokota Jun, Kohno Takashi

Abstract excerpt

Genome scanning at a 1-Mb resolution was undertaken in 29 lung cancer cell lines to clarify the distribution of homozygous (i.e., both allele) deletions along lung cancer genomes, using a high-resolution single nucleotide polymorphism array. Eighteen regions, including two known tumor suppressor loci, CDKN2A at 9p21 and FHIT at 3p14, were found homozygously deleted. Frequencies of deletions at the 18 regions were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16114034
DOI: 10.1002/gcc.20253

Genes

FHIT
PTPRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer.PMID 16114034Read ↗

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