Article
Deficient DNA repair of triple helix-directed double psoralen damage in human cells.
FEBS letters - 30 Oct 1995
Sandor Z, Bredberg A
Abstract excerpt
Damage induced by a single psoralen-modified triple helix-forming oligonucleotide has been reported to be efficiently repaired in human cells. In this study we investigated a set of psoralen coupled oligonucleotides introducing multiple lesions into the target DNA. A simian virus 40 (SV40) shuttle vector was in vitro treated with different triple helix-forming oligonucleotides and UVA radiation, leading to double...
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