Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular spectrum of mutations induced at the HPRT locus by a cross-linking agent in human cell lines with different repair capacities.

Mutation research - 1 Aug 1993

Papadopoulo D, Laquerbe A, Guillouf C, Moustacchi E

Abstract excerpt

Molecular characterization of mutations photoinduced by a cross-linking agent, 4,5',8-trimethylpsoralen (Me3Pso), in normal human lymphoblasts was conducted in parallel with lymphoblasts derived from Fanconi anemia patients. Such cells have been previously described to be impaired in repair of psoralen photolesions. The endogenous HPRT locus was used as a target gene. The treatment of cells with Me3Pso in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Line
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Repair

Share to Lymphocytes

Share to Molecular Sequence Data

Share to Mutation

Share to Ultraviolet Rays

Source

Identifiers

PMID: 7687009
DOI: 10.1016/0921-8777(93)90025-c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular spectrum of mutations induced at the HPRT locus by a cross-linking agent in human cell lines with different repair capacities.PMID 7687009Read ↗

The mutagenic processing of psoralen photolesions leaves a highly specific signature at an endogenous human locus.Semantic proximity Read ↗

HPRT gene expression differs in mutants derived from normal and Fanconi anemia cells: analysis of spontaneous and psoralen-photoinduced mutants.Semantic proximity Read ↗

Genotoxic potential of psoralen cross-links versus monoadducts in normal human lymphoblasts.Semantic proximity Read ↗

Decreased mutagenicity in Fanconi's anemia lymphoblasts following treatment with photoactivated psoralens.Semantic proximity Read ↗

Correlation of UV-induced mutational spectra and the in vitro damage distribution at the human hprt gene.Semantic proximity Read ↗

Biochemical and photochemical mechanisms that produce different UV-induced mutation spectra.Semantic proximity Read ↗

Molecular analysis of ultraviolet-induced mutations in a xeroderma pigmentosum cell line.Semantic proximity Read ↗

Molecular bases of hprt mutations in malathion-treated human T-lymphocytes.Semantic proximity Read ↗

Triplex targeted genomic crosslinks enter separable deletion and base substitution pathways.Semantic proximity Read ↗

Determination of point mutational spectra of benzo[a]pyrene-diol epoxide in human cells.Semantic proximity Read ↗

Lethal and mutagenic effects photoinduced in haploid yeast (Saccharomyces cerevisiae) by two new monofunctional pyridopsoralens compared to 3-carbethoxypsoralen and 8-methoxypsoralen.Semantic proximity Read ↗

Molecular changes in UV-induced and gamma-ray-induced mutations in human lymphoblastoid cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.