Article
A casein-kinase-2-related protein kinase is tightly associated with the large T antigen of simian virus 40.
European journal of biochemistry - 1 Oct 1995
Götz C, Koenig M G, Issinger O G, Montenarh M
Abstract excerpt
The simian virus 40 (SV40) large T antigen is a multifunctional protein involved in SV40 cell transformation and lytic virus infection. Some of its activities are regulated by interaction with cellular proteins and/or by phosphorylation of T antigen by various protein kinases. In this study, we s...
Topics
- Amino Acid Sequence
- Antigens, Polyomavirus Transforming
- Casein Kinase II
- Cell Line, Transformed
- Cell Transformation, Viral
- Humans
- Molecular Sequence Data
- Mutation
- Peptides
- Phosphorylation
- Protein Serine-Threonine Kinases
- Recombinant Proteins
- Simian virus 40
- Substrate Specificity
- Temperature