Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics.

doi:10.1038/nm0795-654

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Article

Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics.

Nature medicine - 1 Jul 1995

Tiihonen J, Kuikka J, Bergström K, Hakola P, Karhu J, Ryynänen O P, Föhr J

Abstract excerpt

Animal studies suggest that development of substance dependence is associated with dopaminergic activity in striatum and the limbic system. Several genetic studies indicate that allele A1 is associated with both D2 receptor density and alcoholism, although these findings have remained controversial. We studied striatal dopamine (DA) re-uptake site densities in 48 subjects (19 healthy controls, 19 habitually...

Topics

Adult
Alcoholism
Alleles
Basal Ganglia
Carrier Proteins
Cocaine
Corpus Striatum
Crime
Dopamine Plasma Membrane Transport Proteins
Female
Humans
Iodine Radioisotopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Membrane Glycoproteins

Membrane Transport Proteins

Mental Disorders

Middle Aged

Nerve Tissue Proteins

Source

Open in PubMed

Identifiers

PMID: 7585146
DOI: 10.1038/nm0795-654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7585146-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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