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Article

The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers.

Molecular psychiatry - 1 May 1998

Pohjalainen T, Rinne J O, Någren K, Lehikoinen P, Anttila K, Syvälahti E K, Hietala J

Abstract excerpt

Positron emission tomography (PET) studies have revealed significant interindividual variation in dopamine D2 receptor density in vivo in human striatum. Low D2 receptor binding in vivo has been found to associate with alcohol/substance dependence. It has been suggested that the A1 allele of human D2 receptor gene might be associated to a specific type of alcoholism and possibly to a reduced D2 receptor density...

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Identifiers

PMID: 9672901
DOI: 10.1038/sj.mp.4000350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers.PMID 9672901Read ↗

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