Article
D2 dopamine receptor polymorphism and brain regional glucose metabolism.
American journal of medical genetics - 18 Apr 1997
Noble E P, Gottschalk L A, Fallon J H, Ritchie T L, Wu J C
Abstract excerpt
Positron emission tomography (PET) studies have shown decreased glucose metabolism in brain regions of detoxified alcoholics and cocaine abusers. However, it is not clear whether this decrease is due to chronic drug abuse or a pre-existing condition. Molecular genetic studies have found an association of the D2 dopamine receptor (DRD2) A1 allele with alcoholism and drug abuse. Moreover, reduced central...
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