Article
The A1 allele of the D2 dopamine receptor gene is associated with high dopamine transporter density in detoxified alcoholics.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Laine T P, Ahonen A, Räsänen P, Pohjalainen T, Tiihonen J, Hietala J
Abstract excerpt
The A1 allele of TaqI A restriction fragment length polymorphism (RFLP) in the D2 receptor (DRD2) gene locus has been suggested to be associated with low D2 receptor density in man. Striatal dopamine transporter (DAT) densities were studied with [(123)I]2-beta-carbometoxy-3beta(4-iodophenyl)tropane and single-photon emission tomography in 29 detoxified alcoholics, who were also genotyped for the two alleles of...
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