Article
D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele.
Pharmacogenetics - 1 Dec 1997
Thompson J, Thomas N, Singleton A, Piggott M, Lloyd S, Perry E K, Morris C M, Perry R H, Ferrier I N, Court J A
Abstract excerpt
The relationship between a dopamine D2 receptor genetic polymorphism at the Taq1 A locus and the level of D2 receptor binding was investigated in normal, middle aged to elderly subjects with no psychiatric or neurological disorders. D2 receptor binding was measured by autoradiography in the cauda...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Corpus Striatum
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptors, Dopamine D2
- Taq Polymerase