Article
Availability of the serotonin transporter in patients with alcohol dependence.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Mar 2011
Ho Pei-Shen, Shih Mei-Chen, Ma Kuo-Hsing, Huang Wen-Sheng, Ho Kellen Kai-Jen, Yen Che-Hung, Lu Ru-Band, Huang San-Yuan
Abstract excerpt
OBJECTIVES: Evidence has suggested that the serotonin transporter (SERT) plays a role in the pathogenesis of alcohol dependence, anxiety and depression and that polymorphisms of the serotonin-transporter-linked promoter region (5-HTTLPR) may influence the SERT. This study evaluated the differences in SERT availability between healthy controls and alcoholic patients and the impact of 5-HTTLPR polymorphisms on SERT...
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