Article
Genotype influences in vivo dopamine transporter availability in human striatum.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 2000
Heinz A, Goldman D, Jones D W, Palmour R, Hommer D, Gorey J G, Lee K S, Linnoila M, Weinberger D R
Abstract excerpt
In vivo availability of striatal dopamine transporter (DAT) protein has been reported to be reduced among alcoholics, and allelic variation of the DAT gene (SLC6A3) has been associated with severity of alcohol withdrawal. We examined the VNTR polymorphism of the 3' untranslated region of SLC6A3 and DAT protein availability in 14 abstinent alcoholics and 11 control subjects. Single photon emission computed...
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