Article
Long-PCR of the ANP gene and PCR-SSCP analysis of the proximal promoter region of the ANP gene in patients with aldosterone producing adenoma.
Biochemical and biophysical research communications - 4 Oct 1995
Tunny T J, Richardson K A, Moriarty C C, Klemm S A, Stowasser M, Gordon R D
Abstract excerpt
Previous studies have shown a significant association between allelic frequencies at the ANP gene locus and aldosterone responsiveness to angiotensin in aldosterone-producing adenoma (APA). We searched for any gross insertions or deletions in the ANP gene in APA and any associations between allelic frequencies at the Hpa II and Sca I RFLP sites within the ANP gene and angiotensin-responsive and unresponsive APA...
Topics
- Adenoma
- Adrenal Cortex Neoplasms
- Aldosterone
- Atrial Natriuretic Factor
- Base Sequence
- DNA
- Deoxyribonucleases, Type II Site-Specific
- Humans
- Molecular Sequence Data
- Mutation